The field of oncology is undergoing a paradigm shift, moving from conventional, one-size-fitsall treatments toward personalized and targeted therapeutic strategies. This work, “PRECISION ONCOLOGY: INNOVATIONS IN DIAGNOSIS, DRUG DELIVERY, AND PATIENT CARE”, seeks to capture the essence of this transformation by exploring the scientific advancements and clinical practices that are redefining cancer care. The aim is to present a comprehensive overview of how precision approaches are shaping diagnostic accuracy, enhancing therapeutic delivery, and prioritising holistic, patient-centred outcomes. This study emphasises the integration of molecular profiling, biomarker-driven therapies, and state-of-the-art drug delivery systems that have enabled oncologists to tailor treatments to the unique genetic and clinical profiles of patients. It also highlights the growing importance of patient well-being, survivorship, and equity in access to innovative cancer care. By bridging research insights with clinical applications, the work aspires to contribute to the broader understanding of how innovations in precision oncology can transform healthcare delivery. The preparation of this work has been both a challenging and rewarding journey. It required extensive engagement with interdisciplinary literature spanning molecular biology, pharmaceutical sciences, clinical oncology, and patient-care frameworks. I hope this contribution provides useful insights to researchers, practitioners, and students interested in the evolving landscape of precision oncology. Finally, this preface reflects my aspiration to shed light on the potential of precision oncology not only as a scientific advancement but also as a patient-centric approach that holds promise for more effective, equitable, and compassionate cancer treatment in the future. Thank You Dr. Sanjeev Kumar Dr. Sanjana Bhagat Dr. Sumit Bhatt Dr. Farah Deeba