This volume outlines the proceedings of the conference on "Quadratic Forms and Their Applications" held at University College Dublin. It includes survey articles and research papers ranging from applications in topology and geometry to the algebraic theory of quadratic forms and its history. Various aspects of the use of quadratic forms in algebra, analysis, topology, geometry, and number theory are addressed. Special features include the first published proof of the Conway-Schneeberger Fifteen Theorem on integer-valued quadratic forms and the first English-language biography of Ernst Witt, founder of the theory of quadratic forms.