Beer of Broadway Fame

by Alfred W. McCoy

2016 · State University of New York Press

Finalist for the 2016 Foreword INDIES Book of the Year Award in the Regional category For more than a century, New York City was the brewing capital of America, with more breweries producing more beer than any other city, including Milwaukee and St. Louis. In Beer of Broadway Fame, Alfred W. McCoy traces the hundred-year history of the prominent Brooklyn brewery, Piel Bros., and provides an intimate portrait of the company's German American family. Through quality and innovation Piel Bros. grew from Brooklyn's smallest brewery in 1884, producing only 850 kegs, into the sixteenth-largest brewery in America, brewing over a million barrels by 1952. Through a narrative spanning three generations, McCoy examines the demoralizing impact of pervasive US state surveillance during World War I and the Cold War, as well as the forced assimilation that virtually erased German American identity from public life after World War I. McCoy traces Piel Bros.'s changing fortunes from its early struggle to survive in New York's Gilded Age beer market, the travails of Prohibition with police raids and gangster death threats, to the crushing competition from the big national brands after World War II. Through a fusion of corporate records with intimate personal correspondence, McCoy reveals the social forces that changed a great city, the US brewing industry, and the country's economy.

Drug Delivery Strategies for Poorly Water-Soluble Drugs

by Dionysios Douroumis, Alfred Fahr

2012 · John Wiley & Sons

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self–microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer- drug conjugates, polymeric micelles, and mesoporous silica nanoparticles. For each approach the book discusses the main instrumentation, operation principles and theoretical background, with a focus on critical formulation features and clinical studies. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues. Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials.

The Emergence of Oligopoly

by Alfred S. Eichner

2019 · JHU Press

Originally published in 1969. In describing the emergence of oligopoly, Professor Eichner has written a history of the American sugar refining industry, one based in part on records of the United States Department of Justice. Sugar refining was one of the first major industries to be consolidated, and its expertise was in many ways typical of the development of other industries. Eichner's focus is on the changing pattern of industrial organization. This study is based on a unique four-stage model of the process by which the industrial structure of the American economy has evolved. The first part of the book traces the early history of the sugar refining industry and argues that the classical model of a competitive industry is inherently unstable once large fixed investments are required. The more closely sugar refining approximated this model, the more unstable the model became in practice. This instability led, in 1887, to the formation of the sugar trust. The author contends that the trust was formed not to exploit economies of scale but with the intent of achieving control over prices. In the second part of the book, Eichner describes the political and legal reaction that transformed monopoly into oligopoly. This sequence of events is best understood in terms of a learning curve in which the response of businessmen over time was related to the changing institutional environment in which they were forced to operate.

The Historiography of Genocide

by Anton Weiss-Wendt, Robert Krieken, Alfred A. Cave, Ben Kiernan, Doris Bergen, David Moshman, Victoria Sanford, John Docker, Robert Hitchcock

2008 · Springer

The Historiography of Genocide is an indispensable guide to the development of the emerging discipline of genocide studies and the only available assessment of the historical literature pertaining to genocides.