Books by "David R. Horwitz"
6 books found
Optical Coherence Tomography Angiography of the Eye
by David Huang, Bruno Lumbroso, Yali Jia, Nadia Waheed
2024 · CRC Press
Optical coherence tomography (OCT) angiography is an important new imaging modality that is already being used by ophthalmologists in retina centers worldwide. It uses motion as intrinsic contrast, thus obviating the need to inject any intravenous dye. It uses infrared light that is invisible to the patient, and only requires few seconds per scan. This makes it both easier to use and much better tolerated by patients than traditional dye-based fluorescein angiography (FA) and indocyanine green (ICG) angiography. Inside Optical Coherence Tomography Angiography of the Eye Drs. David Huang, Bruno Lumbroso, Yali Jia, and Nadia Waheed include detailed information on clinical applications and fundamental principles needed to understand and use this new technology. This includes information on high-speed OCT systems, algorithms to extract flow contrast, the appearance of the normal eye, the findings in myriad diseases, and tips on how to deal with artifact and pitfalls. The 3-dimensional nature of OCT angiography provides visualization that was not possible before with either FA or ICG and readers will come to appreciate how this enables the visualization of previously difficult to image vascular beds such as the 4 retinal vascular plexuses (radial peripapillary, superficial, intermediate, and deep), the choriocapillaris, and the deeper choroidal vessels. Given its noninvasive nature and ease of use, OCT angiography imaging is rapidly taking an important place in everyday ophthalmology and may soon replace fluorescein angiography in everyday practice. Optical Coherence Tomography Angiography of the Eye is designed to be the definitive text on this cutting-edge technology for the retina specialist and comprehensive ophthalmologist.
Nineteenth-century European thought, especially in Germany, was increasingly dominated by a new historicist impulse to situate every event, person, or text in its particular context. At odds with the transcendent claims of philosophy and--more significantly--theology, historicism came to be attacked by its critics for reducing human experience to a series of disconnected moments, each of which was the product of decidedly mundane, rather than sacred, origins. By the late nineteenth century and into the Weimar period, historicism was seen by many as a grinding force that corroded social values and was emblematic of modern society's gravest ills. Resisting History examines the backlash against historicism, focusing on four major Jewish thinkers. David Myers situates these thinkers in proximity to leading Protestant thinkers of the time, but argues that German Jews and Christians shared a complex cultural and discursive world best understood in terms of exchange and adaptation rather than influence. After examining the growing dominance of the new historicist thinking in the nineteenth century, the book analyzes the critical responses of Hermann Cohen, Franz Rosenzweig, Leo Strauss, and Isaac Breuer. For this fascinating and diverse quartet of thinkers, historicism posed a stark challenge to the ongoing vitality of Judaism in the modern world. And yet, as they set out to dilute or eliminate its destructive tendencies, these thinkers often made recourse to the very tools and methods of historicism. In doing so, they demonstrated the utter inescapability of historicism in modern culture, whether approached from a Christian or Jewish perspective.
The Future of the Nursing Workforce in the United States
by Peter Buerhaus, Douglas Staiger, David Auerbach
2009 · Jones & Bartlett Publishers
The Future of the Nursing Workforce in the United States: Data, Trends and Implications provides a timely, comprehensive, and integrated body of data supported by rich discussion of the forces shaping the nursing workforce in the US. Using plain, jargon free language, the book identifies and describes the key changes in the current nursing workforce and provide insights about what is likely to develop in the future. The Future of the Nursing Workforce offers an in-depth discussion of specific policy options to help employers, educators, and policymakers design and implement actions aimed at strengthening the current and future RN workforce. The only book of its kind, this renowned author team presents extensive data, exhibits and tables on the nurse labor market, how the composition of the workforce is evolving, changes occurring in the work environment where nurses practice their profession, and on the publics opinion of the nursing profession.
Targeting Protein Kinases for Cancer Therapy
by David J. Matthews, Mary E. Gerritsen
2011 · John Wiley & Sons
An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.
One of our great urbanists and one of our great public health experts join forces to reckon with how cities are changing in the face of existential threats the pandemic has only accelerated Cities can make us sick. They always have—diseases spread more easily when more people are close to one another. And disease is hardly the only ill that accompanies urban density. Cities have been demonized as breeding grounds for vice and crime from Sodom and Gomorrah on. But cities have flourished nonetheless because they are humanity’s greatest invention, indispensable engines for creativity, innovation, wealth, and connection, the loom on which the fabric of civilization is woven. But cities now stand at a crossroads. During the global COVID crisis, cities grew silent as people worked from home—if they could work at all. The normal forms of socializing ground to a halt. How permanent are these changes? Advances in digital technology mean that many people can opt out of city life as never before. Will they? Are we on the brink of a post-urban world? City life will survive but individual cities face terrible risks, argue Edward Glaeser and David Cutler, and a wave of urban failure would be absolutely disastrous. In terms of intimacy and inspiration, nothing can replace what cities offer. Great cities have always demanded great management, and our current crisis has exposed fearful gaps in our capacity for good governance. It is possible to drive a city into the ground, pandemic or not. Glaeser and Cutler examine the evolution that is already happening, and describe the possible futures that lie before us: What will distinguish the cities that will flourish from the ones that won’t? In America, they argue, deep inequities in health care and education are a particular blight on the future of our cities; solving them will be the difference between our collective good health and a downward spiral to a much darker place.