ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS

by DR A. BHARATH KUMAR, DR. JITEN MISHRA, MR. DIGAMBAR BISOI, DR. MADHU SAHU

Advanced Biopharmaceutics & Pharmacokinetics is born out of a desire to provide a comprehensive and integrated understanding of the principles that govern the fate of drugs in the human body. In the rapidly evolving world of pharmaceutical sciences, the ability to accurately predict, assess, and apply pharmacokinetic and biopharmaceutical data is not only vital for drug development but also critical in clinical decision-making and personalized medicine. This book aims to bridge the gap between theoretical foundations and practical applications, offering a nuanced perspective tailored for students, educators, researchers, and professionals. Over the years, pharmacokinetics has emerged as a cornerstone in drug discovery and development, influencing every stage from preclinical studies to post-marketing surveillance. At the same time, the principles of biopharmaceutics—dealing with the absorption, distribution, metabolism, and excretion of drugs—have proven essential in understanding drug performance and therapeutic outcomes. Recognizing the intertwined nature of these disciplines, this book brings them together in a cohesive narrative, enriched with real-world case studies, graphical models, equations, and problem-solving approaches. This book has been written keeping in mind the curriculum needs of undergraduate and postgraduate students in pharmacy and related fields. However, its practical orientation and research-based content make it equally useful for industry professionals involved in formulation, clinical pharmacology, and regulatory affairs. Numerous illustrative examples, practice questions, and reference materials have been incorporated to make the learning experience more interactive and insightful. As scientific knowledge continues to advance, it is hoped that this book serves as a reliable resource and foundational guide for all those seeking to deepen their understanding of drug kinetics and biopharmaceutical principles. I welcome feedback and suggestions from readers that could help improve future editions and enhance the utility of this work. DR A. BHARATH KUMAR DR. JITEN MISHRA MR. DIGAMBAR BISOI DR MADHU SAHU