Biotransformations in Organic Chemistry

by Kurt Faber

2017 · Springer

This well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts—principles of stereoselective transformations, enzyme properties and kinetics—the different types of reactions are explained according to the 'reaction principle', such as hydrolysis, reduction, oxidation, C–C bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques, artificial enzymes and the design of cascade-reactions are treated in a separate section. A final chapter deals with the basic rules for the safe and practical handling of biocatalysts. The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry. Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale. In this 7th edition new topics have been introduced which include alcohol and amine oxidases, amine dehydrogenases, imine reductases, haloalkane dehalogenases, ATP-independent phosphorylation, Michael-additions and cascade reactions. This new edition also emphasizes the use of enzymes in industrial biotransformations with practical examples.

Attachment to Pets

by Henri Julius, Andrea Beetz, Kurt Kotrschal, Dennis Turner, Kerstin Uvnäs-Moberg

2012 · Hogrefe Publishing GmbH

The biological and psychological basis of pet therapy / animal-assisted therapy and what this means for practice "A comprehensive, scientific foundation for human-animal therapy." (Judith Solomon) In recent years, the ancient symbiosis between humans and their pets has entered a new phase, marked by the burgeoning clinical specialty of human-animal therapy. This approach uses the relationship between humans and their (mainly) mammalian pets to support the growth of emotion regulation, social skills, and mental health in children, adolescents, and adults. But how are humans and animals able to develop close bonds at all? What makes it possible for animals to have a therapeutic effect on humans? And how can we best use this understanding in animal-assisted therapy? In this unique book, a team of expert biologists and psychologists integrate and combine sophisticated biological and psychological knowledge to answer these questions. Together they have created a comprehensive, scientific foundation for human-animal therapy, a foundation that will facilitate the development, implementation, and evaluation of effective new interventions.