Books by "Mark D. Brewer"
5 books found
Mild Cognitive Impairment and Dementia
by Glenn E. Smith, Mark W. Bondi
2013 · Oxford University Press
In 2011, National Institute on Aging and Alzheimer's Association joint task forces released proposed criteria for Alzheimer' disease diagnosis. These proposals included revisions to the nearly 30-year-old NINDS-ADRDA criteria for Alzheimer's diagnosis and added criteria for diagnosis of Mild Cognitive Impairment (MCI) due to Alzheimer's disease. The same year the American Psychiatric Association proposed new criteria for major and minor neurocognitive disorders (the entities previously known as dementia and mild cognitive impairment, respectively). These new criteria reflect the research and clinical advances in identifying mild cognitive impairment and offer new opportunities for prevention, treatment, and management of neurodegenerative conditions. A major focus of this book is on the mild cognitive impairment prodrome of the common dementias. In addition to discussing the most common neurodegenerative conditions, many rare neurodegenerative conditions are highlighted. Most chapters include an autopsy-confirmed case presentation from the authors' files. Following the case presentation, those chapters present current diagnostic criteria, epidemiology, neuropathology/neurophysiology, genetics, neuroimaging studies as relevant, associated clinical features, differential neuropsychological features and possible interventions for each disorder. The pace of change in research and practice in the field of normal cognitive aging and dementia is increasing almost as fast as the median age of the population. The massive baby boom population bubble is currently entering the age of risk for neurodegenerative conditions. Neuropsychologists will play a major role in refining and applying these diagnoses, and in developing, testing, and refining interventions for these diagnoses, and in caring for this population. This book is intended to prepare neuropsychologists and others interested in neuropsychology to serve this fastest growing segment of our population.
An ideal resource for both pediatricians and endocrinologists, Sperling's Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today's clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical practice. Whether you're preparing for certification or have extensive clinical experience, this detailed, authoritative reference helps you increase your knowledge and determine the best possible course for every patient. - Delivers trusted guidance in every area of the field: including Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests. - Features new topics such as transgender issues in children and adolescents and endocrinology of pregnancy, the fetus and the placenta. - Offers expert coverage of hot topics such as disorders of sexual development, molecular basis of endocrine disorders, hypoglycemia in newborns and infants; neonatal and other monogenic forms of diabetes; Type I and Type II diabetes and their treatment with new insulins together with the progress in an artificial pancreas and new medications for T2DM in adolescents; the obesity epidemic and role of bariatric surgery; and advances toward personalized medicine. - Includes easy-to-follow algorithms and numerous quick-reference tables and boxes in every clinical chapter, plus interactive questions online for self-assessment. - Offers state-of-the-art information and fresh perspectives from new and award-winning authors in such areas as disorders of growth, multiple endocrine tumors, and puberty and its disorders in girls and boys.
An ancestral trail through two English counties inhabited by everyday, church-going country folk. Great-grandmother Mary Brewer Andrew was to grow up in a sheltered Cornish village founded by a Welsh saint, but fate found her transported across the country to Suffolk, where she was to find the man of her dreams and start an idyllic family. Life was good and prosperous as a butcher's wife, the only real tragedy being in WWII with the loss of her youngest child. Yet her own childhood and ancestry tell a tale of death and hardship. Pealing back the pages of the lives of her immediate parents' family, who were agricultural labourers, is a story unto itself. Some ancestors did run successful businesses though. They were millers; but even millers can fall foul of the law, which has necessitated a detailed look into the life inside the notorious Bodmin jail. Chilling though its stories are, the place is now a museum, a skylight looking down into how things should not have been, but how history & karma affect us all.
Handbook of Statistical Systems Biology
by Michael Stumpf, David J. Balding, Mark Girolami
2011 · John Wiley & Sons
Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book: Provides a comprehensive account of inference techniques in systems biology. Introduces classical and Bayesian statistical methods for complex systems. Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems. Discusses various applications for statistical systems biology, such as gene regulation and signal transduction. Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies. Presents an in-depth presentation of reverse engineering approaches. Provides colour illustrations to explain key concepts. This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.
Mastering PC Troubleshooting & Operating Systems
by MARK JOHN LADO
2025 · Amazon Digital Services LLC - Kdp
The third edition of Mastering PC Troubleshooting and Operating Systems is your ultimate guide to navigating the evolving world of PC systems. This updated and comprehensive resource addresses the challenges and opportunities in troubleshooting modern hardware, operating systems, and next-generation technologies, making it an indispensable tool for IT professionals, students, and tech enthusiasts alike. With the rapid growth of AI, machine learning, quantum-ready devices, and hybrid work environments, the complexity of PC systems has reached unprecedented levels. This book equips readers with the latest strategies, tools, and techniques for diagnosing and resolving even the most complex issues. Covering hardware, software, networking, and cybersecurity, it combines real-world scenarios with practical, actionable solutions to ensure readers stay ahead of the curve. Key Features: In-Depth Coverage of PC Troubleshooting: Learn to tackle issues in advanced hardware, including liquid cooling systems, GPU-accelerated workstations, 3D-stacked memory, and quantum-ready devices. AI and Machine Learning Integration: Discover how AI-driven diagnostics and predictive maintenance tools are revolutionizing troubleshooting in both hardware and software systems. Future-Ready Operating Systems: Gain insights into the evolution of operating systems, cloud-native platforms, and real-time diagnostics with predictive analytics. Comprehensive Networking Solutions: Explore cutting-edge approaches to optimizing Wi-Fi 7 networks, troubleshooting 5G-enabled devices, and ensuring connectivity in hybrid and edge computing environments. Cybersecurity Essentials: Learn how to identify and mitigate threats, from ransomware attacks to insider vulnerabilities, with AI-powered tools and behavioral analytics. Focus on Emerging Technologies: Address challenges in mixed reality, IoT synchronization, blockchain networking, and wearable tech troubleshooting. Practical Case Studies and Examples: Benefit from real-world scenarios that illustrate modern failures, solutions, and best practices. Who Should Read This Book? Whether you’re an IT professional, a student pursuing a career in tech, or simply a tech enthusiast looking to deepen your knowledge, this book is for you. It offers both foundational knowledge and advanced techniques, making it suitable for all levels of expertise. What You’ll Learn: How to use AI and machine learning tools for automated diagnostics and real-time monitoring. Effective strategies for addressing compatibility issues in cross-platform devices and hybrid systems. The importance of sustainability in hardware design and repair. Tips for diagnosing VR/AR hardware issues and optimizing PC performance for mixed-reality applications. Advanced troubleshooting methods for virtualized environments, including VMs, containers, and hybrid cloud setups. Why Choose This Book? With detailed explanations, comprehensive assessments, and forward-thinking insights, this third edition is designed to prepare readers for the challenges of troubleshooting in 2025 and beyond. Each chapter concludes with a thorough assessment to reinforce learning and ensure mastery of key concepts. Whether you’re diagnosing power supply issues, debugging operating system kernels, or tackling cybersecurity vulnerabilities, this book provides the knowledge and tools needed to solve problems efficiently and effectively. If you’re ready to master the art and science of PC troubleshooting and take your skills to the next level, this book is your ultimate companion. Get your copy today and stay ahead in the ever-changing world of PC technology!