4 books found
by F. William Orr, Michael R. Buchanan, Leonard Weiss
2024 · CRC Press
Although mechanisms involved in the spread of cancer have been the subject of a major research endeavor over the past decade, metastatic tumors still account for significant clinical morbidity and the failure of cancer treatment. Not only are the vascular pathways the most common route for the dissemination of cancer cells, but interactions between the cells and the circulation act as important rate-regulators for the metastatic process. This authoritative, multi-authored volume addresses the importance of microcirculation in cancer metastasis. The book begins with up-to-date reviews on the biology of endothelial cells and the structure and physiology of the normal and tumor microcirculations, and then emphasizes interactions between components of the microcirculation and cancer cells. Metastasis is discussed through chapters exploring the entry of cancer cells into the circulation, the biophysics and morphology of cancer cell traffic and arrest, interactions with host cells and the basement membranes, and angiogenesis. This fascinating book will interest oncologists, pathologists, and students of metastasis or the microcirculation.
by K. E. Britton, David Collier, Michael Maisey, Q. H. Siraj
2013 · Springer
Nuclear medicine is the bridge between a particular clinical problem and a relevant test using radionuclides. It began as a minor technical tool used in a few branches of medicine, notably endocrinology and nephrology. However, throughout the world it has now become established as a clinical discipline in its own right, with specific training programmes, special skills and a particular approach to patient management. Although the practising nuclear medicine physician must necessarily learn a great deal of basic science and technology, a sound medical training and a clinical approach to the subject remains of fundamental importance. It is for this reason that we have attempted in this book to approach the subject from a clinical standpoint, including where necessary relevant physiological material. There exist many excellent texts which cover the basic science and technology of nuclear medicine. We have, therefore, severely limited our coverage of these aspects of the subject to matters which we felt to be essential, particularly those which have been less well covered in other texts - for example, the contents of Chapter 21 on Quantitation by Royal and McNeil. Similarly, we have included at the end of some chapters descriptions of particular techniques where we and the authors felt that it would be helpful. In order to emphasize the clinical approach of this book we have inverted the traditional sequence of material in chapters, presenting the clinical problems first in each instance.
Gold Medal Winner, Human Resources and Employee Training, 2012 Axiom Business Book Awards Trust, Pride and Camaraderie—transform your company into a "Great Place to Work" The Great Place to Work Institute develops the annual ranking of the Fortune 100 Best Companies to Work For. In this book, the authors explore the model of a Great Place to Work For-one which fosters employee trust, pride in what they do, and enjoyment in the people they work with. They answer the fundamental question, "What is the business value of creating a great workplace?" and brings the definition of a Great Place to work alive with anecdotes, best practices, and quotes from employees working at the best workplaces in the U.S. Reveals the essential ingredients in and the trends of the best places to work Explores Great Place to Work model developed in 1984 and validated through its enduring resonance in both the United States and in over 40 countries around the world Written by Michael Burchell and Jennifer Robin two Great Place to Work Institute Insiders If you organization is struggling with the challenges of leveraging human capital, discover why some companies have what it takes to be great.
The law relating to general defences is one of the most important areas in the criminal law, yet the current state of the law in the United Kingdom reveals significant problems in the adoption of a consistent approach to their doctrinal and theoretical underpinnings, as exemplified by a number of recent developments in legislation and case law. A coherent and joined-up approach is still missing. This volume provides an analysis of the main contentious areas in British law, and proposes ways forward for reform. The collection includes contributions from leading experts across various jurisdictions. Part I examines the law in the United Kingdom, with specialist contributions on Irish and Scottish law. Part II consists of contributions by authors from a number of foreign jurisdictions, all written to a common research grid for maximum comparability, which provide a wider background of how other legal systems treat problems relating to general defences in the context of the criminal law, and which may serve as points of reference for domestic law reform.