Military Food Engineering and Ration Technology

by Ann H. Barrett, Armand Vincent Cardello

2012 · DEStech Publications, Inc

Written by a team from the U.S. Army's Combat Feeding Directorate at the Natick Research, Development and Engineering Center, this technical volume represents a comprehensive guide to how the military designs, processes, customizes, packages and distributes highly palatable, long shelf-life food products for field personnel. The book offers new data on numerous technologies used to solve problems such as nutrient densification, lightweighting, novel thermal processing, and long-term quality preservation in delivering appetizing foods and more. Testing techniques are explained for evaluating sensory qualities of foods and their effects on physical and cognitive performance.

Observer-Based Fault Diagnosis and Fault-Tolerant Control for Switched Systems

by Dongsheng Du, Shengyuan Xu, Vincent Cocquempot

2020 · Springer Nature

This book focuses on the fault diagnosis observer design for the switched system. Model-based fault diagnosis and fault tolerant control are one of the most popular research directions in recent decades. It contains eight chapters. Every chapter is independent in the method of observer design, but all chapters are around the same topic. Besides, in each chapter, the model description and theoretical results are firstly provided, then some practical application examples are illustrated to prove the obtained results. The advanced theoretical methodologies will benefit researchers or engineers in the area of safety engineering and the arrangement of the structure will help the readers to understand the content easily.

Single-Molecule Studies of Nucleic Acids and Their Proteins

by David Bensimon, Vincent Croquette, Jean-François Allemand, Xavier Michalet, Terence Strick

2018 · Oxford University Press

This book provides the basis for understanding the elastic properties of nucleic acids (DNA, RNA), the methods used to manipulate them (e.g. optical, magnetic and acoustic tweezers and traps), and how to observe their interactions with proteins (e.g. fluorescence microscopy, FCS, FRET, etc.). It then exemplifies the use of these various methods in the study of three families of DNA enzymes: polymerases, helicases and topoisomerases. The book aims not to be exhaustive, but rather to stimulate the imagination of readers in the application of these single molecule approaches to the study of DNA/RNA and their interactions.

Strategies and Tactics in Organic Synthesis

by Michel Miesch, Tania Welsch, Vincent Rietsch, Laurence Miesch

2013 · Elsevier Inc. Chapters

This chapter describes various syntheses of hamigeran B. Different methodologies were developed, and for our part, we achieved a formal synthesis of (±)-hamigeran B involving an intramolecular alkynylogous Mukaiyama aldol reaction promoted by dual Lewis acid activation as a key step. This unexpected reaction was discovered by treating a ketone with TBSOTf/NEt3 in order to obtain the corresponding silyl enol ether, which, in fact, evolves toward a new type of intramolecular aldol reaction. Fortunately, the study of the scope and limitations of this reaction allowed us to set up an original synthetic route to hamigeran B. Our results indicated clearly that serendipity plays a key role in the development of original strategies in organic synthesis.

Active Biohybrid Nanostructures For Biomedical Applications

by Vincent Mauricio Kadiri

2022 · Cuvillier Verlag

Nanostructures, especially biohybrid nanostructures have long been imagined as promising carriers in (bio)medical applications such as drug and gene delivery. However, few nanomedical applications, apart from liposomes, have seen widespread adoption. All available biomedical nanosystems to date rely on passive diffusion for their dispersal and very few studies demonstrate chemical targeting. Nature, on the other hand, has evolved many ways of combining highly specific targeting and active microscale motion, e.g., chemotaxis, magnetotaxis, and phototaxis of bacteria and microorganisms. In order to realize synthetic nanostructures and systems that can rival natural ones, a number of challenges still lie ahead of us. In this thesis, the author introduces examples of bioinspired and biohybrid nanostructures that address some of these challenges. Two material platforms are developed in this thesis, one based on M13 bacteriophages and one on FePt-based nanomotors. These systems can be viewed as very different but equally promising active biohybrid nanostructures. The introduced active biohybrid nanostructures are completely biocompatible and in the case of FePt nanodevices also enable precise actuated motion and targeting. The tools presented in this thesis are general and may help in the development of new biohybrid nanodevices for biomedical applications and therapies.